Health and Nutrition

Dietary Supplements

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Food & Agrochemicals

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Analytical Standards

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The Health and Nutrition division at CEIMIC consists of a complex of Human and Animal Health Service Laboratories, bringing together more than 100 professionals in a laboratory area exceeding

2000m2,comprised of three main business units: 

CEIMIC ACCERT

Specialized in analytical services tailored to the Pharmaceuticals and veterinary markets, including quality control and stability studies, research, development, and validation of specific-purpose analytical methods, and the local manufacturing of high-purity Analytical Standards.

CEIMIC SGB

Focused on the veterinary, human, and animal nutrition markets, SGB operates in the development and validation of analytical methods, quality control, physicochemical assays, and stability studies.

CEIMIC FOOD

Specialized in the analysis of pesticide residues in food, mycotoxins, and heavy metals testing, among others. 

 

The complex offers innovative scientific solutions across chemistry, pharmacy, and biotechnology, backed by international accreditations and full regulatory compliance.

Pharma

The pharmaceutical area is one of the main pillars of CEIMIC HEALTH AND NUTRITION, offering comprehensive quality control, research, and development services for Active Pharmaceutical Ingredients (API) and finished pharmaceutical products (medicines).

Offered Services 

Extractables and Leachables Studies

 Execution of comprehensive testing in accordance with USP <1663>, <1664>, <1664.1>, PQRI, or internal protocols.

Nitrosamines Analysis

  • Analysis of nitrosamines and other genotoxic substances in APIs and finished products.

  • Full compliance with RDC 677/2022 issued by the Agência Nacional de Vigilância Sanitária (ANVISA).

  • Includes exploratory analysis using high-resolution mass spectrometry (HRMS).

  • Critical assessment for the presence of nitrosamines.

Cleaning Validation

Cleaning validation assays according to RDC 301/2019 and IN 138/2022 (ANVISA).

Assay and Impurities Testing

  • Determination of active ingredient content via high-performance liquid chromatography (HPLC-UV, HPLC-RID, UHPLC-DAD, UHPLC-ELSD).
  • Impurity analysis using HPLC and UHPLC with various detectors.
  • Gas chromatography (GC-FID, GC-MS, HS-GC-MS).
  • Coupled mass spectrometry (UHPLC-MS, UHPLC-MS/MS).

Method Development and Validation

  • Development of analytical methods according to RDC 166/2017 (ANVISA).
  • Validation based on international guidelines (ICH Q2B, FDA Guidance for Industry).
  • Chemical investigation of unknown impurities.

Stability Studies

  • Execution of stability studies according to RDC 318/2019 (ANVISA).
  • Forced degradation studies according to RDC 964/2025 (ANVISA).
  • International guidelines (ICH Q1A, Q1B, Q2B), utilizing stability-indicating methods.

Dissolution Studies

  • Development of dissolution methods in accordance with RDC 31/2010 and Guide 14/2018.
  • Solubility studies.

Physicochemical Assays

  • Full chemical characterization (FT-IR, H-NMR, C-NMR, MS, MS/MS, HRMS).
  • Chromatographic and titrimetric assays.
  • Thermal analysis (TGA, DSC).
  • Loss on drying and Karl Fischer titration.
  • Determination of elemental impurities (ICP-MS, ICP-OES, AA) according to USP <232> and <233>.

Registration of Medicines

  • Various studies to support the registration of medicines for human use.
  • Compliance with RDC 753/2022 (ANVISA).

Quality Control of Actives and Impurities

  • Antibiotics: Amoxicillin, ampicillin, cephalexina, cefoperazone, ceftriaxone, ciprofloxacin, cloxacillin, colistin, among many others.

  • Antiparasitics: Abamectin, albendazole, closantel, ivermectin, mebendazole, among many others.

  • Anti-inflammatories: Carprofen, ketoprofen, meloxicam, piroxicam, among many others.

  • Antifungals: Ketoconazole, clotrimazole, fluconazole, itraconazole, among many others.

  • Antihistamines: Chlorpheniramine, loratadine, among many others.

  • Anesthetics: Ketamine hydrochloride, tiletamine hydrochloride, zolazepam, among many others.

  • Hormones: Estradiol benzoate, estradiol cypionate, buserelin, ethinylestradiol, among many others.

  • Vitamins and Nutrients: Ascorbic acid, folic acid, biotin, niacin, calcium pantothenate, vitamins A, B1, B2, B6, B12, D2, D3, E, K2, K3, among many others.

  • Other miscellaneous active ingredients.

Extractables and Leachables Studies

 Execution of comprehensive testing in accordance with USP <1663>, <1664>, <1664.1>, PQRI, or internal protocols.

Nitrosamines Analysis

  • Analysis of nitrosamines and other genotoxic substances in APIs and finished products.

  • Full compliance with RDC 677/2022 issued by the Agência Nacional de Vigilância Sanitária (ANVISA).

  • Includes exploratory analysis using high-resolution mass spectrometry (HRMS).

  • Critical assessment for the presence of nitrosamines.

Cleaning Validation

Cleaning validation assays according to RDC 301/2019 and IN 138/2022 (ANVISA).

Assay and Impurities Testing

  • Determination of active ingredient content via high-performance liquid chromatography (HPLC-UV, HPLC-RID, UHPLC-DAD, UHPLC-ELSD).
  • Impurity analysis using HPLC and UHPLC with various detectors.
  • Gas chromatography (GC-FID, GC-MS, HS-GC-MS).
  • Coupled mass spectrometry (UHPLC-MS, UHPLC-MS/MS).

Method Development and Validation

  • Development of analytical methods according to RDC 166/2017 (ANVISA).
  • Validation based on international guidelines (ICH Q2B, FDA Guidance for Industry).
  • Chemical investigation of unknown impurities.

Stability Studies

  • Execution of stability studies according to RDC 318/2019 (ANVISA).
  • Forced degradation studies according to RDC 964/2025 (ANVISA).
  • International guidelines (ICH Q1A, Q1B, Q2B), utilizing stability-indicating methods.

Dissolution Studies

  • Development of dissolution methods in accordance with RDC 31/2010 and Guide 14/2018.
  • Solubility studies.

Physicochemical Assays

  • Full chemical characterization (FT-IR, H-NMR, C-NMR, MS, MS/MS, HRMS).
  • Chromatographic and titrimetric assays.
  • Thermal analysis (TGA, DSC).
  • Loss on drying and Karl Fischer titration.
  • Determination of elemental impurities (ICP-MS, ICP-OES, AA) according to USP <232> and <233>.

Registration of Medicines

  • Various studies to support the registration of medicines for human use.
  • Compliance with RDC 753/2022 (ANVISA).

Quality Control of Actives and Impurities

  • Antibiotics: Amoxicillin, ampicillin, cephalexina, cefoperazone, ceftriaxone, ciprofloxacin, cloxacillin, colistin, among many others.

  • Antiparasitics: Abamectin, albendazole, closantel, ivermectin, mebendazole, among many others.

  • Anti-inflammatories: Carprofen, ketoprofen, meloxicam, piroxicam, among many others.

  • Antifungals: Ketoconazole, clotrimazole, fluconazole, itraconazole, among many others.

  • Antihistamines: Chlorpheniramine, loratadine, among many others.

  • Anesthetics: Ketamine hydrochloride, tiletamine hydrochloride, zolazepam, among many others.

  • Hormones: Estradiol benzoate, estradiol cypionate, buserelin, ethinylestradiol, among many others.

  • Vitamins and Nutrients: Ascorbic acid, folic acid, biotin, niacin, calcium pantothenate, vitamins A, B1, B2, B6, B12, D2, D3, E, K2, K3, among many others.

  • Other miscellaneous active ingredients.

Accreditations and Certifications

ACCREDITATION UNIT SCOPE
REBLAS ANVISA ACCERT Active Pharmaceutical Ingredients (API), medicines, Cannabis products, food.
NBR ISO/IEC 17025:2017 ACCERT Pharmaceutical raw material (assay and impurities by HPLC), finished pharmaceutical product (assay by HPLC), analysis of nitrosamines in APIs.
ANVISA BPL ACCERT Good Laboratory Practices (GLP) in Bioequivalence and Bioavailability (bioanalytical stage).
MAPA ACCERT, SGB Quality control in pharmaceutical products (physicochemical assays), stability studies.
NBR ISO 9001:2015 SGB Research and development of analytical methods, quality control analysis for pharmaceutical products.
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Veterinary and Animal Nutrition

The veterinary and animal nutrition division encompasses specialized analytical services for veterinary products, veterinary pharmaceuticals, animal feed, and Dietary Supplements for animals.

Offered Services

Physicochemical Assays

  • General physicochemical assays according to specific protocols.

  • Determination of mineral content using Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES), and Atomic Absorption Spectrophotometry (AA).

  • Elemental impurities testing (ICP-MS, ICP-OES, AA).

  • Analysis of coefficient of variation [Cv (Mn)] in mix, premix, and other matrices.

  • Quality control via High-Performance Liquid Chromatography (HPLC) and Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).

Animal Nutrition Analysis

  • Mineral analysis in animal feed samples.

  • Determination of vitamin content in feed and premix.

  • Free and total amino acid analysis.

  • Fatty acid profile testing (full profile, saturated, monounsaturated, polyunsaturated, trans fats).

  • Quantification of triglycerides.

  • Fiber analysis (Neutral Detergent Fiber [NDF], Acid Detergent Fiber [ADF], crude fiber).

  • Total reducing sugars analysis.

Veterinary Stability Studies

  • Stability studies for active ingredients and veterinary pharmaceuticals in compliance with the Ministério da Agricultura e Pecuária (MAPA) of Brazil.

  • Physicochemical assays and stability studies for veterinary raw materials and finished products.

Cleaning Validation

  • Cleaning validation testing for veterinary manufacturing facilities according to MAPA guidelines.

  • Pharmaceutical cleaning validation assays pursuant to RDC 301/2019 and IN 138/2022 issued by the Agência Nacional de Vigilância Sanitária (ANVISA).

Method Development and Validation

  • Forced degradation studies in accordance with RDC 964/2025 (ANVISA) and international guidelines (ICH Q1A, Q1B, Q2B).

  • Analytical method development and validation pursuant to RDC 166/2017 (ANVISA), national MAPA regulations, and international standards (ICH Q2B, FDA Guidance for Industry).

Technical Consulting

  • Technical consultancy for regulatory inquiries and filings with MAPA.

  • Monitoring, execution, and statistical data treatment for laboratories.

  • Factorial design for process optimization in analytical workflows.

Quality Control of Actives and Impurities

  • Antiparasitics: Abamectin, amitraz, cypermethrin, deltamethrin, ivermectin, levamisole, oxantel, pyrantel.

  • Coccidiostats: Amprolium, clopidol, decoquinate, nicarbazin, salinomycin, toltrazuril.

  • Antimicrobials: Apramycin, avilamycin, bacitracin, colistin, enrofloxacin, florfenicol, tilmicosin.

  • Antioxidants: BHA, BHT.

  • Preservatives: Propionic acid, sodium benzoate, piperonyl butoxide.

  • Nutritional Additives: Carnitine, acetylcarnitine, choline, betaine.

  • Vitamins: Ascorbic acid, folic acid, biotin, niacin, calcium pantothenate, vitamins A, B1, B2, B6, B12, D2, D3, E, K2, K3.

  • Amino Acids: Alanine, arginine, cysteine, phenylalanine, glycine, glutamate, histidine, isoleucine, leucine, lysine, methionine, proline, serine, tyrosine, threonine, tryptophan, valine.

  • Fatty Acids: Comprehensive fatty acid profile (C4 to C25). 

Physicochemical Assays

  • General physicochemical assays according to specific protocols.

  • Determination of mineral content using Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES), and Atomic Absorption Spectrophotometry (AA).

  • Elemental impurities testing (ICP-MS, ICP-OES, AA).

  • Analysis of coefficient of variation [Cv (Mn)] in mix, premix, and other matrices.

  • Quality control via High-Performance Liquid Chromatography (HPLC) and Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).

Animal Nutrition Analysis

  • Mineral analysis in animal feed samples.

  • Determination of vitamin content in feed and premix.

  • Free and total amino acid analysis.

  • Fatty acid profile testing (full profile, saturated, monounsaturated, polyunsaturated, trans fats).

  • Quantification of triglycerides.

  • Fiber analysis (Neutral Detergent Fiber [NDF], Acid Detergent Fiber [ADF], crude fiber).

  • Total reducing sugars analysis.

Veterinary Stability Studies

  • Stability studies for active ingredients and veterinary pharmaceuticals in compliance with the Ministério da Agricultura e Pecuária (MAPA) of Brazil.

  • Physicochemical assays and stability studies for veterinary raw materials and finished products.

Cleaning Validation

  • Cleaning validation testing for veterinary manufacturing facilities according to MAPA guidelines.

  • Pharmaceutical cleaning validation assays pursuant to RDC 301/2019 and IN 138/2022 issued by the Agência Nacional de Vigilância Sanitária (ANVISA).

Method Development and Validation

  • Forced degradation studies in accordance with RDC 964/2025 (ANVISA) and international guidelines (ICH Q1A, Q1B, Q2B).

  • Analytical method development and validation pursuant to RDC 166/2017 (ANVISA), national MAPA regulations, and international standards (ICH Q2B, FDA Guidance for Industry).

Technical Consulting

  • Technical consultancy for regulatory inquiries and filings with MAPA.

  • Monitoring, execution, and statistical data treatment for laboratories.

  • Factorial design for process optimization in analytical workflows.

Quality Control of Actives and Impurities

  • Antiparasitics: Abamectin, amitraz, cypermethrin, deltamethrin, ivermectin, levamisole, oxantel, pyrantel.

  • Coccidiostats: Amprolium, clopidol, decoquinate, nicarbazin, salinomycin, toltrazuril.

  • Antimicrobials: Apramycin, avilamycin, bacitracin, colistin, enrofloxacin, florfenicol, tilmicosin.

  • Antioxidants: BHA, BHT.

  • Preservatives: Propionic acid, sodium benzoate, piperonyl butoxide.

  • Nutritional Additives: Carnitine, acetylcarnitine, choline, betaine.

  • Vitamins: Ascorbic acid, folic acid, biotin, niacin, calcium pantothenate, vitamins A, B1, B2, B6, B12, D2, D3, E, K2, K3.

  • Amino Acids: Alanine, arginine, cysteine, phenylalanine, glycine, glutamate, histidine, isoleucine, leucine, lysine, methionine, proline, serine, tyrosine, threonine, tryptophan, valine.

  • Fatty Acids: Comprehensive fatty acid profile (C4 to C25). 

Specific Animal Nutrition Testing

ACTIVE / PARAMETER Matrix ANALYTICAL TECHNIQUE
Total Fatty Acids Raw material, premix, animal feed, food Gravimetric
Fatty Acid Profile Raw material, premix, animal feed, food GC-MS
Free Amino Acids Raw material, premix, animal feed, food HPLC
Vitamins Raw material, premix, animal feed, food HPLC
Minerals Animal feed, food ICP-MS, ICP-OES, AA
Toxins (Mycotoxins) Raw material, premix, animal feed, food ELISA

Accreditations and Certifications

ACCREDITATION Unit scope
NBR ISO 9001:2015 SGB Research and development of analytical methods, quality control testing for veterinary products, stability studies, animal nutrition testing.
MAPA ACCERT, SGB Quality control in pharmaceutical/veterinary products (physicochemical assays), stability studies.
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Medical Devices

With a solid track record in this sector, we provide specialized services such as extractables and leachables studies in packaging and contact materials, ensuring the safety, efficacy, and full regulatory compliance of your products.

Offered Services

Extractables and Leachables Studies

  • Analysis of substances with the potential to migrate from packaging and contact materials.

  • Compliance with United States Pharmacopeia (USP) chapters <1663>, <1664>, <1664.1>, Product Quality Research Institute (PQRI) guidelines, or internal protocols.

  • Applicable to medical devices and their packaging systems.

Cleaning Validation

  • Cleaning validation testing pursuant to RDC 301/2019 issued by the Agência Nacional de Vigilância Sanitária (ANVISA).

  • Applicable to manufacturing equipment and contact surfaces associated with medical devices.

Physicochemical Assays

  • Comprehensive physicochemical characterization of contact materials.
  • Material compatibility testing.

Relevant Accreditations and Certifications

  • NBR ISO/IEC 17025:2017 (CEIMIC ACCERT)
  • REBLAS ANVISA (CEIMIC ACCERT)
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Dietary Supplements

The dietary supplements sector encompasses specialized analytical services for human nutritional supplementation products, including vitamins, minerals, amino acids, and other functional ingredients.

Offered Services

Active Ingredient Testing

  • Determination of vitamin content via High-Performance Liquid Chromatography (HPLC).

  • Mineral analysis via Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES), and Atomic Absorption Spectrophotometry (AA).

  • Determination of amino acids via HPLC.

  • Fatty acid analysis via Gas Chromatography-Mass Spectrometry (GC-MS).

  • Bioactive compound analysis (polyphenols, flavonoids, etc.).

Stability Studies

  • Stability studies for dietary supplements pursuant to RDC 843/2024 issued by the Agência Nacional de Vigilância Sanitária (ANVISA).

  • Compliance with IN 281/2024 (ANVISA).

  • Forced degradation studies.

Physicochemical Assays

  • Determination of moisture and volatile matter.

  • Ash content analysis.

  • pH determination.

  • Density testing.

  • Dissolution testing.

  • Particle size distribution (granulometry).

Safety Testing

  • Elemental impurities determination (ICP-MS, ICP-OES, AA).

  • Residual solvents analysis.

  • Pesticide residue testing (when applicable).

  • Mycotoxin analysis (when applicable).

Method Development and Validation

  • Analytical method development pursuant to RDC 166/2017 (ANVISA).

  • Validation based on international guidelines (ICH Q2B).

Vitamin and Nutrient Portfolio

Vitamins

  • Vitamin A

  • Vitamin B1 (thiamine)

  • Vitamin B2 (riboflavin)

  • Vitamin B6 (pyridoxine)

  • Vitamin B12 (cobalamin)

  • Vitamin C (ascorbic acid)

  • Vitamin D2 (ergocalciferol)

  • Vitamin D3 (cholecalciferol)

  • Vitamin E (tocopherol)

  • Vitamin K2 (menaquinone)

  • Vitamin K3 (menadione)

  • Folic acid

  • Biotin

  • Niacin (vitamin B3)

  • Calcium pantothenate (pantothenic acid)

Amino Acids

  • Alanine

  • Arginine

  • Aspartate

  • Cysteine

  • Phenylalanine

  • Glycine

  • Glutamate

  • Glutamine

  • Histidine

  • Isoleucine

  • Leucine

  • Lysine

  • Methionine

  • Proline

  • Serine

  • Tyrosine

  • Threonine

  • Tryptophan

  • Valine 

Other Nutrients

  • Essential fatty acids

  • Minerals (calcium, magnesium, iron, zinc, etc.)

  • Bioactive compounds

Accreditations and Certifications

Accreditation / Certification Unit Scope
REBLAS ANVISA ACCERT Food (includes Dietary Supplements)
NBR ISO/IEC 17025:2017 ACCERT Quality control testing
NBR ISO 9001:2015 SGB Quality control testing for supplements
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Food and Agrochemicals

The food and agrochemicals sector encompasses specialized analytical services for testing pesticide residues, chemical contaminants, mycotoxins, and other quality and safety parameters in food products, animal feed, and agrochemical products.

Food Testing Services

Pesticide Analysis

  • Polar and non-polar pesticide analysis.

  • Multi-residue determination via Gas Chromatography-Tandem Mass Spectrometry (GC-MS/MS).

  • Multi-residue determination via Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).

  • Dithiocarbamate determination via GC-MS/MS.

  • Polar pesticide determination via LC-MS/MS.

  • Compliance testing for Maximum Residue Limits (MRL) and Acute Reference Dose (ARfD / Acceptable Daily Intake).

Elemental Impurities Analysis

  • Heavy metal testing in food matrices.

  • Instrumentation: Inductively Coupled Plasma Mass Spectrometry (ICP-MS) and Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES). 

Mycotoxin Testing

  • Mycotoxin assays in food products.

  • Analytical technique: Enzyme-Linked Immunosorbent Assay (ELISA).

  • Mycotoxins tested:

    • Total aflatoxins (LOQ: 1 ppb).

    • Ochratoxin (LOQ: 2 ppb).

    • T-2 toxin (LOQ: 20 ppb).

    • Zearalenone (LOQ: 25 ppb).

    • Fumonisin (LOQ: 250 ppb).

    • Deoxynivalenol / Vomitoxin (LOQ: 250 ppb). 

Acrylamide Analysis

Determination and quantification of acrylamide in processed foods.

Additional Testing Services

  • Elemental impurities testing.

  • Residual solvent testing.

  • Chemical contaminant analysis. 

Animal Nutrition and Food Analysis

Nutritional Composition Testing

  • Fatty acid profile testing (comprehensive profile).

  • Amino acid analysis.

  • Vitamin analysis.

  • Mineral analysis.

  • Fiber testing (Neutral Detergent Fiber [NDF], Acid Detergent Fiber [ADF], crude fiber). 

Contaminant Analysis

  • Toxin analysis (mycotoxins).

  • Pesticide analysis (when applicable).

  • Residual solvent analysis.

  • Residual disinfectant testing. 

Physicochemical Assays

General physicochemical assays according to specific protocols.

Food and Agrochemicals Portfolio

Pesticides Analyzed

  • Polar and non-polar pesticides.

  • Pesticide multi-residues.

  • Dithiocarbamates.

  • Organophosphate pesticides.

  • Pyrethroid pesticides. 

Contaminants Analyzed

  • Heavy metals (cadmium, lead, mercury, arsenic).

  • Mycotoxins (aflatoxins, ochratoxin, T-2 toxin, zearalenone, fumonisin, deoxynivalenol).

  • Residual solvents.

  • Acrylamide. 

Nutritional Components

  • Fatty acids (saturated, monounsaturated, polyunsaturated, trans fats).

  • Free amino acids.

  • Vitamins.

  • Minerals.

  • Dietary fibers. 

Accreditations and Certifications

Accreditation / Certification Unit Scope
REBLAS ANVISA FOOD, ACCERT Food
NBR ISO/IEC 17025:2017 FOOD Multi-residue determination via GC-MS and LC-MS, dithiocarbamates, polar pesticides
MAPA SGB Quality control (physicochemical assays), stability studies
NBR ISO 9001:2015 SGB Quality control testing for food and animal nutrition
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Analytical Standards

The Analytical Standards division encompasses the manufacturing, development, and commercialization of Chemical Reference Substances (CRS) and high-quality Analytical Standards, utilized in quality control testing as well as research and development (R&D) across diverse industries.

Analytical Standards Manufacturing

CEIMIC ACCERT has been locally manufacturing Analytical Standards since 2011, achieving its first export in 2011 to Germany and Switzerland. Currently, it holds a portfolio of over 4,000 developed Analytical Standards and maintains approximately 300 standards in continuous stock.

Categories of Standards Offered

Nitrosamine Standards

API Impurity Standards

  • Impurities of Active Pharmaceutical Ingredients (APIs).

  • Custom synthesis according to client requirements.

API Standards

  • Pure Active Pharmaceutical Ingredients (APIs).

  • Premium quality certification with analytical traceability.

Solvent Standards

  • Residual solvents.

  • Synthesis solvents.

  • Process solvents.

Amino Acid Standards

  • Essential and non-essential amino acids.

  • Certified analytical purity.

Sugar Standards

  • Monosaccharides.

  • Disaccharides.

  • Polysaccharides.

Reagent and Intermediate Standards

  • Synthesis reagents.

  • Chemical intermediates.

Custom Synthesis

  • On-demand development of Analytical Standards.

  • Innovative synthetic routes.

  • Process solvent characterization.

Nitrosamine Standards

API Impurity Standards

  • Impurities of Active Pharmaceutical Ingredients (APIs).

  • Custom synthesis according to client requirements.

API Standards

  • Pure Active Pharmaceutical Ingredients (APIs).

  • Premium quality certification with analytical traceability.

Solvent Standards

  • Residual solvents.

  • Synthesis solvents.

  • Process solvents.

Amino Acid Standards

  • Essential and non-essential amino acids.

  • Certified analytical purity.

Sugar Standards

  • Monosaccharides.

  • Disaccharides.

  • Polysaccharides.

Reagent and Intermediate Standards

  • Synthesis reagents.

  • Chemical intermediates.

Custom Synthesis

  • On-demand development of Analytical Standards.

  • Innovative synthetic routes.

  • Process solvent characterization.

Track Record and Capacity

  • 2011: First export of Analytical Standards (Germany and Switzerland).
  • 2015: Expansion into the Brazilian and Latin American markets.
  • 2018-2019: Rapid development of nitrosamine Analytical Standards during regulatory shifts.
  • 2021: Participation in synthesis route development projects for COVID-19 Pharmaceuticals.
  • Current: Portfolio of 4,000+ Analytical Standards with 300 maintained in continuous stock.

Analytical Standards Features

Regulatory Compliance

  • Compliant with criteria established by RDC 166/2017 issued by the Agência Nacional de Vigilância Sanitária (ANVISA)
  • Accompanied by Certificate of Analysis (CoA)
  • Comprehensive Characterization Report
  • Safety Data Sheet (SDS / FISPQ)
  • Compliance with international standards

Premium Quality

  • Certified purity
  • Complete traceability
  • Validated analytical methods

Supply Security

  • Continuous stock of 300 Analytical Standards
  • Fast and reliable delivery
  • Specialized technical support

Applications of Analytical Standards

CEIMIC ACCERT Analytical Standards are utilized across various industries:

  • • Pharmaceuticals: Quality control
  • • Veterinary: Product testing
  • • Food Industry: Contaminants and additives
  • • Agrochemicals: Pesticides and herbicides
  • • Environmental: Monitoring
  • • Chemical Industry: Synthesis and R&D
  • • Biotechnology: Novel product development

Accreditations and Credentials

Accreditation / Standard Scope
RDC 166/2017 (ANVISA) Manufacturing of Chemical Reference Substances (Analytical Standards)
NBR ISO/IEC 17025:2017 Testing and characterization of Analytical Standards
REBLAS ANVISA Quality assurance and analytical traceability
ISO 17034 (in development) Certification of Reference Materials (CRM)

Characterization Methodologies

Analytical Standards are characterized using high-complexity analytical methodologies to ensure accuracy, precision, and reliability:

Chromatography
HPLC, UHPLC, GC, GC-MS, LC-MS, LC-MS/MS
Spectroscopy
FT-IR, ¹H-NMR, ¹³C-NMR, MS, MS/MS, HRMS
Thermal Analysis
TGA, DSC
Titrametric Assays
Karl Fischer, Acid-base titrations
Physicochemical Assays
Melting/boiling point, density, solubility

Executive Summary of Business Areas

 

Area Unit Core Services Key Accreditations
Pharmaceuticals ACCERT Quality control, analytical method validation, nitrosamine testing. REBLAS, ISO/IEC 17025, ANVISA GLP
Veterinary and Animal Nutrition SGB Nutritional testing, stability studies, veterinary product control. ISO 9001, MAPA
Medical Devices ACCERT Extractables and leachables testing, cleaning validation. ISO/IEC 17025, REBLAS
Dietary Supplements ACCERT/SGB Vitamins/minerals testing, stability studies, method validation. REBLAS, ISO/IEC 17025, ISO 9001
Food and Agrochemicals FOOD/SGB Pesticides residue testing, mycotoxins, contaminants. REBLAS, ISO/IEC 17025, ISO 9001
Analytical Standards ACCERT Manufacturing of Chemical Reference Substances, custom synthesis, certification. RDC 166 (ANVISA), ISO/IEC 17025, ISO 17034*

Infrastructure and Technology

Analytical Equipment Fleet

The CEIMIC laboratory complex features state-of-the-art technology to ensure maximum sensitivity, precision, and accuracy in every assay:

  • • Liquid Chromatography: HPLC (UV, RID), UHPLC (DAD, ELSD, MS, MS/MS)
  • • Gas Chromatography: GC-FID, GC-MS, HS-GC-MS
  • • Spectrometry / Spectroscopy: ICP-MS, ICP-OES, AA, HRMS, FT-IR, ¹H/¹³C-NMR
  • • Thermal Analysis: TGA, DSC
  • • Physicochemical Testing: Brookfield Viscometer, Refractometer, Densitometer
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